Grupa E Valencia - Chelsea Londra 1-1 (Soldado 87'-penalti / Lampard 56') Bayer Leverkusen - RKC Genk 2-0 (Bender 29', Ballack 90')

Grupa F

Arsenal Londra - Olympiakos 2-1 (Chamberlain 8', Santos 20' / Fuster 27')
Marseille - Borussia Dortmund 3-0 (Ayew 20' si 69'-penalti, Remy 62')

Grupa G

Zenit - FC Porto 3-1 (Sirokov 20' si 63', Danny 72' / James 10')
Sahtior Donetk - APOEL Nicosia 1-1 (Jadson 64' / Trickovski 61')

Grupa H

BATE Borisov - FC Barcelona 0-5 (Volodko 19'-autogol, Pedro 22', Messi 38' si 55', Villa 90')
AC Milan - Viktoria Plzen 2-0 (Ibrahimovici 53'-penalti, Cassano 66')