Qarabag - Borussia Dortmund 0-1 (Barrios 90'), in tur 0-4 Maritimo - BATE Borisov 1-2 (Kanu 90' / Pavlov 52', Skavysh 90), in tur 0-3 Lokomotiv Moscova - Lausanne 1-1 (Aliyev 85' / Silvio 17'), 3-4 la penaltiuri, in tur 1-1 Dnepr Mogilev - Villarreal 1-2 (Yurchenko 19' / Nilmar 45', Ruben 90), in tur 0-5

Dinamo Minsk - FC Brugge 2-3 (Chukhlei 47', Dragun 90' / Hoefkens 5'-penalti si 32'-penalti, Dalmat 26'), in tur 1-2
Aktobe - AZ Alkmaar 2-1 (Tleshev 67' si 88' / Wernbloom 10')
HJK Helsinki - Besiktas 0-4 (Quaresma 15', Guti 67', Uysal 77', Holosko 90'), in tur 0-2
Metalist Harkov - Omonia Nicosia 2-2 (Devici 66', Xavier 71' / Leandro 60' si 64'), in tur 1-0

Brondby - Sporting Lisabona 0-3 (Evaldo 45', Coelho 75', Djalo 90'), in tur 2-0
Austria Viena - Aris Salonic 1-1 (Linz 56' / Ruiz 41'), in tur 0-1
APOEL - Getafe 1-1 dupa prelungiri (Almeida 41' / Salomou 98'), in tur 0-1
UNIREA URZICENI - Hajduk Split 1-1 (Bilasco 2' / Vukusici 88'), in tur 1-4

Trabzonspor - Liverpool 1-2 (Gutierrez 4' / Kacar 83'-autogol, Kuyt 88'), in tur 0-1
PSV Eindhoven - Sibir 5-0 (Berg 38', Engelaar 56', Toivonen 64', Dzsudzsak 73' si 90'-penalti), in tur 0-1
Litex Loveci - Debrecen 1-2 (Niflore 68' / Mbengono 53', Czvitkovics 81'), in tur 0-2
Levski Sofia - AIK Stockholm 2-1 (Mladenov 49', Dembele 51' / Bangura 11'), in tur 0-0

Grasshopper - STEAUA 1-0 (Salatici 77'), 3-4 la penaltiuri, in tur 0-1
VfB Stuttgart - Slovan 2-2 (Gebhart 56', Gentner 64' / Dobrotka 9', Sylvestr 53'), in tur 1-0
Tavriya - Bayer Leverkusen 1-3 (Idahor 5'-penalti / Vidal 50'-penalti, Golaydo 74'-autogol, Castro 90'), in tur 0-3
Maccabi Tel Aviv - PSG 4-3 (Atar 48' si 90', Avidor 68', Medunjanin 83'-penalti / Hoarau 40'-penalti, Giuly 64', Nene 90'-penalti), in tur 0-2

Gent - Feyenoord 2-0 (Soumahoro 34', Coulibaly 61'), in tur 0-1
AEK Atena - Dundee United 1-1 (Diop 23' / Daly 78'), in tur 0-1
Lech Poznan - Dnepr Dnepropetrovsk 0-0, in tur 1-0
Utrecht - Celtic 4-0 (van Wolfswinkel 11'-penalti, 19'-penalti si 46', Maguire 62'), in tur 0-2

The New Saints - TSKA Sofia 2-2 (Williams 14', Evans 62' / Aquaro 11', Tiboni 80'), in tur 0-3
Motherwell - Odense 0-1 (Utaka 28'), in tur 1-2
Maribor - Palermo 3-2 (Marcos 14', Ilicici 58', Andjelkovici 89' / Hernandez 62' si 68'), in ur 1-2
Manchester City - FC TIMISOARA 2-0 (Wright-Phillips 43', Boyata 59'), in tur 1-0

Lille - FC VASLUI 2-0 (Cabaye 69'-penalti, Chedjou 80'), in tur 0-0
Karpaty Lvov - Galatasaray 1-1 (Fedetskiy 90' / Yilmaz 90'), in tur 2-2
Juventus - Sturm Graz 1-0 (Del Piero 53'), in tur 2-1
Elfsborg - Napoli 0-2 (Cavani 29' si 38'), in tur 0-1

Aston Villa - Rapid Viena 2-3 (Agbonlahor 22', Heskey 77' / Nuhiu 52', Sonnleitner 78', Gartler 81'), in tur 1-1
Dinamo Zagreb - Gyor ETO 2-1 (Sammir 45'-penalti si 84'-penalti / Ceolin 17'), in tur 2-0
Fenerbahce - PAOK Salonic 1-1 dupa prelungiri (Emre 50' / Muslimovici 102'), in tur 0-1
FC Porto - Genk 4-2 (Hulk 36', 59'-penalti si 63', Fernando 53' / Vossen 22' si 56'), in tur 3-0