Grupa A Anderlecht - Ajax 1-1 (Leager '85 / Rommedahl '73) FC Timisoara - Dinamo Zagreb 0-3 (Badelj '8, Sammir '52, Morales '59)

Grupa B
Slavia Praga - Lille 1-5 (Belaid '6 - penalti / Suchy '47 - autogol, Frau '71, Gervinho '85 si '90, Souquet '88)
Valencia - Genoa 3-2 (Silva '52, Zigici '56, Villa '81 - penalti / Floccari '41, Kharja '63 - penalti)

Grupa C
Hamburg - Hapoel Tel-Aviv 4-2 (Berg '5 si '12, Elia '40, Ze Roberto '78 / Shechter '37, Yeboah '62)
Celtic - Rapid Viena 1-1 (McDonald '28 / Jelavic '4)

Grupa D
Sporting Lisabona - Hertha Berlin 1-0 (Silva '17)
Ventspils - Heerenveen 0-0

Grupa E
AS Roma - CSKA Sofia 2-0 (Okaka '19, Perrotta '23)
Fulham - FC Basel 1-0 (Murphy '57)

Grupa F
Dinamo - Panathinaikos 0-1 (Karagounis '79)
Galatasaray - Strum Graz 1-1 (Baros '63 / Beichler '45)

Grupa G
Levski Sofia - Lazio 0-4 (Matuzalem '22, Zarate '45, Meghni '67, Rocchi '73)
Red Bull Salzburg - Villarreal 2-0 (Janko '21, Tchoyi '84)

Grupa H
Twente Enschede - Steaua 0-0
Sheriff - Fenerbahce 0-1 (Alex '53)

Grupa I
AE Atena - Benfica 1-0 (Majstorovic '43)
BATE Borisov - Everton 1-2 (Likhtarovich '16 / Fellaini '68, Cahil '77)

Grupa J
Sahtior Donetk - Partizan Belgrad 4-1 (Lomic '24 - autogol, Adriano '38, Jadson '55, Rakitskiy '67 / Ljajic '87)
Toulouse - FC Brugge 2-2 (Sissoko '55, Cignac '84 / Akpala '53, Perisic '90)

Grupa K
FC Copenhaga - Sparta Praga 1-0 (N'Doye '25)
PSV Eindhoven - CFR Cluj 1-0 (Bakkal '9)

Grupa L
Werder Bremen - Atletico Bilbao 3-1 (Hunt '18, Martins '41, Frings '90 - penalti / Llorente '90)
Austria Viena - Nacional Madeira 1-1 (Schumacher '77 / Micael '35)